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Cellular schwannoma masquerading as malignant peripheral nerve sheath tumour: a diagnostic dilemma
Kiran Alam1, Anshu Jain, Aroonima Misra
1Department of Pathology, JN Medical College, Aligarh, Uttar Pradesh, India.
Abstract:
We present a case of a 15-year-old girl with a pulsatile, rapidly enlarging mass at the root of the nose suspected to be malignant. Excisional biopsy showed worrisome histological features; however, a final diagnosis of cellular schwannoma was reached excluding the possibility of malignant peripheral nerve sheath tumour by histological and immunohistochemical attributes. Cellular schwannoma, a pseudosarcomatous entity, is a rare benign neoplasm that may cause bone erosion and may be mistaken for a malignancy, clinically and histologically. Diagnosis of cellular schwannoma is essential to prevent mismanagement as it never metastasises and responds to local excision as opposed to aggressive treatment required by a malignant neoplasm.
