Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient-Ventilator Interaction During Noninvasive Ventilation.

Respiratory care·2025
Same author

Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial: protocol for a batched, stepped-wedge, cluster-randomised, type 2 hybrid effectiveness-implementation trial.

BMJ open·2025
Same author

Author Response: Let It Breathe: Mastering Spontaneous Breathing Trials.

Respiratory care·2024
Same author

AARC Clinical Practice Guideline: Patient-Ventilator Assessment.

Respiratory care·2024
Same author

Pulse Oximetry: 2023 Year in Review.

Respiratory care·2024
Same author

Statistics for the Non-Statistician: How to Read the Respiratory Care Literature.

Respiratory care·2024

Related Experiment Video

Updated: May 11, 2026

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice
07:55

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice

Published on: May 5, 2011

Noninvasive ventilation for acute respiratory failure.

Dean R Hess1

  • 1Department of Respiratory Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. dhess@partners.org

Respiratory Care
|May 28, 2013
PubMed
Summary

Noninvasive ventilation (NIV) is underutilized despite strong evidence for COPD exacerbations and pulmonary edema. This review covers NIV use in various acute respiratory failure scenarios, emphasizing initiation and failure.

Keywords:
COPDacute cardiogenic pulmonary edemaacute respiratory failurenoninvasive ventilation

More Related Videos

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Related Experiment Videos

Last Updated: May 11, 2026

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice
07:55

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice

Published on: May 5, 2011

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Area of Science:

  • Critical Care Medicine
  • Respiratory Medicine
  • Pulmonology

Background:

  • Noninvasive ventilation (NIV) is gaining interest for acute respiratory failure but remains underutilized.
  • Strong evidence supports NIV for COPD exacerbations and acute cardiogenic pulmonary edema.
  • Evidence for NIV in other acute respiratory failure presentations is varied.

Purpose of the Study:

  • To review the current evidence for NIV use in various acute respiratory failure settings.
  • To highlight the importance of recognizing NIV initiation and failure criteria.
  • To discuss the optimal interface and ventilator considerations for NIV therapy.

Main Methods:

  • Literature review of studies evaluating NIV for acute respiratory failure.
  • Analysis of evidence supporting or refuting NIV use in different clinical scenarios.
  • Discussion of practical aspects including interfaces and ventilator technology.

Main Results:

  • NIV is strongly supported for COPD exacerbations and acute cardiogenic pulmonary edema.
  • Evidence varies for other acute respiratory failure types.
  • Oronasal masks are recommended for initial interface due to comfort and leak prevention.
  • NIV-specific ventilators offer superior leak compensation compared to ICU ventilators.

Conclusions:

  • NIV should be a standard therapy for clinicians managing acute respiratory failure.
  • Appropriate patient selection, interface choice, and monitoring for failure are crucial.
  • The role of NIV outside the ICU setting requires further investigation.