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Updated: May 11, 2026

Unbiased Deep Sequencing of RNA Viruses from Clinical Samples
Published on: July 2, 2016
viRome: an R package for the visualization and analysis of viral small RNA sequence datasets
Mick Watson1, Esther Schnettler, Alain Kohl
1ARK-Genomics, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG. mick.watson@roslin.ed.ac.uk
Summary:
RNA interference (RNAi) is known to play an important part in defence against viruses in a range of species. Second-generation sequencing technologies allow us to assay these systems and the small RNAs that play a key role with unprecedented depth. However, scientists need access to tools that can condense, analyse and display the resulting data. Here, we present viRome, a package for R that takes aligned sequence data and produces a range of essential plots and reports.
Availability And Implementation:
viRome is released under the BSD license as a package for R available for both Windows and Linux http://virome.sf.net. Additional information and a tutorial is available on the ARK-Genomics website: http://www.ark-genomics.org/bioinformatics/virome.
Contact:
mick.watson@roslin.ed.ac.uk.
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