Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 11, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Reoperation after failed resective epilepsy surgery.

Rainer Surges1, Christian E Elger

  • 1Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. rainer.surges@gmail.com

Seizure
|May 29, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Resective temporal lobe surgery in refractory temporal lobe epilepsy: prognostic factors of postoperative seizure outcome.

Journal of neurosurgery·2026
Same author

T1w/T2w Ratio Identifies the Basolateral Amygdala as a Preferential Target in Autoimmune Limbic Encephalitis.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same author

Distinct neuronal populations in the human brain combine content and context.

Nature·2026
Same author

Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks.

Nature neuroscience·2025
Same author

Concept and location neurons in the human brain provide the 'what' and 'where' in memory formation.

Nature communications·2024
Same author

Long-term seizure outcome after epilepsy surgery of neuroglial tumors.

Frontiers in neurology·2024
Same journal

UNC13A-related neurodevelopmental disorders in children: epilepsy phenotypes and antiseizure medication response.

Seizure·2026
Same journal

Switching from oxcarbazepine to eslicarbazepine in patients with focal epilepsy: A systematic review and single-arm meta-analysis.

Seizure·2026
Same journal

Efficacy, tolerability, and EEG lateralization-based predictors of neuropsychiatric adverse events in pediatric SeLECTS treated with perampanel monotherapy.

Seizure·2026
Same journal

Cross-cultural validation of the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE) in Chinese-speaking people with epilepsy.

Seizure·2026
Same journal

Unlocking seizure freedom: A European Delphi panel study on the clinical, humanistic, and economic value of seizure control in epilepsy.

Seizure·2026
Same journal

RLIM variant associated with X-linked epilepsy with neurodevelopmental disorders and the molecular sub-regional effects.

Seizure·2026
See all related articles

Reoperation for intractable focal epilepsy can be effective, with over a third of patients achieving seizure freedom after a second surgery. Careful evaluation of clinical, imaging, and EEG data is key for successful outcomes.

Area of Science:

  • Neurosurgery
  • Epileptology
  • Clinical Neurology

Background:

  • Resective epilepsy surgery offers sustained seizure freedom in up to 80% of selected patients with intractable focal epilepsy.
  • However, a significant proportion of patients do not achieve seizure control after initial surgery, necessitating further evaluation.

Purpose of the Study:

  • To review case series on reoperation after failed resective epilepsy surgery in adults.
  • To identify factors associated with successful outcomes in patients undergoing a second epilepsy surgery.

Main Methods:

  • Systematic literature review of 15 case series on reoperation after failed resective epilepsy surgery.
  • Analysis of outcomes and complications in 402 reoperated adult patients.

Main Results:

Keywords:
Epilepsy surgeryFrontal lobe epilepsyHippocampal sclerosisHypothalamic hamartomaTemporal lobe epilepsy

More Related Videos

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Related Experiment Videos

Last Updated: May 11, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

  • 3.8-14% of patients undergo reoperation, with an average of 2-5.5 years between surgeries.
  • 36.6% of reoperated patients achieved seizure freedom. Complications occurred in 13.5%, primarily visual field defects.
  • Causes of initial failure included incorrect localization, incomplete resection, or additional foci. Concordant post-surgical imaging and electroclinical findings predicted success.

Conclusions:

  • Reoperation for epilepsy is an efficacious and safe option for selected patients with failed initial surgery.
  • Thorough assessment of clinical, imaging, and EEG data is crucial for successful reoperation and sustained seizure control.