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Updated: May 11, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Ischemic mitral regurgitation: mechanisms, intraoperative echocardiographic evaluation, and surgical considerations
John M Connell1, Andrea Worthington, Frederick Y Chen
1Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Abstract:
Ischemic mitral regurgitation (IMR) is a subcategory of functional rather than organic, mitral valve (MV) disease. Whether reversible or permanent, left ventricular remodeling creates IMR that is complex and multifactorial. A comprehensive TEE examination in patients with IMR may have important implications for perioperative clinical decision making. Several TEE measures predictive of MV repair failure have been identified. Current practice among most surgeons is to typically repair the MV in patients with IMR. MV replacement is usually reserved for situations in which the valve cannot be reasonably repaired, or repair is unlikely to be tolerated clinically.
Insights
Ischemic mitral regurgitation (IMR) is a complex condition resulting from left ventricular remodeling. Transesophageal echocardiography (TEE) helps guide surgical decisions for mitral valve repair or replacement in IMR patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Echocardiography
Background:
- Ischemic mitral regurgitation (IMR) is a functional mitral valve (MV) disease.
- Left ventricular remodeling is a complex, multifactorial cause of IMR.
- TEE plays a crucial role in assessing IMR and guiding perioperative decisions.
Purpose of the Study:
- To highlight the implications of Transesophageal Echocardiography (TEE) in managing Ischemic Mitral Regurgitation (IMR).
- To identify TEE measures that predict mitral valve (MV) repair failure in IMR patients.
- To discuss current surgical strategies for IMR, including repair and replacement.
Main Methods:
- Comprehensive Transesophageal Echocardiography (TEE) examination.
- Identification of TEE measures predictive of MV repair failure.
- Review of current surgical practices for IMR management.
Main Results:
- Several TEE measures have been identified as predictive of MV repair failure in IMR.
- TEE provides critical information for perioperative decision-making in IMR patients.
- Understanding these TEE findings influences the choice between MV repair and replacement.
Conclusions:
- Comprehensive TEE is essential for evaluating patients with IMR.
- TEE can predict the likelihood of successful mitral valve repair.
- Surgical management of IMR involves a careful consideration of repair versus replacement based on TEE findings.
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