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Related Experiment Video

Updated: May 11, 2026

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

In vivo minimally invasive interstitial multi-functional microendoscopy.

Asaf Shahmoon1, Shiran Aharon, Oded Kruchik

  • 1Clinical Photonics Laboratory, School in Advanced Optical Technologies (SAOT), Erlangen 91052, Germany. Asaf.Sh11@gmail.com

Scientific Reports
|May 29, 2013
PubMed
Summary

This study presents a new 200 μm microendoscope for minimally invasive internal organ imaging and blood hemoglobin monitoring. The device offers high resolution, enabling visualization of features less than 1 μm.

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Last Updated: May 11, 2026

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High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
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High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging

Published on: January 11, 2011

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Minimally Invasive Technologies

Background:

  • Internal organ imaging is crucial for disease diagnosis and monitoring.
  • Current minimally invasive techniques face limitations in resolution and functionality.
  • There is a need for advanced endoscopic tools for detailed in-vivo examination.

Purpose of the Study:

  • To introduce a novel multi-functional microendoscope for high-resolution, minimally invasive imaging.
  • To demonstrate the microendoscope's capability for local hemoglobin concentration measurement.
  • To evaluate the device's potential for previously inaccessible clinical applications.

Main Methods:

  • Development of a microendoscope with an external diameter of 200 μm.
  • Integration of high-resolution imaging capabilities (over 5,000 pixels, <1 μm spatial resolution).
  • In-vitro and in-vivo testing in rat models.

Main Results:

  • The microendoscope successfully performed high-resolution imaging of internal structures.
  • The device demonstrated feasibility for monitoring hemoglobin concentration in blood vessels.
  • Successful in-vitro and in-vivo validation confirmed device performance.

Conclusions:

  • The developed microendoscope is a powerful tool for high-resolution, minimally invasive imaging.
  • This technology opens possibilities for new clinical modalities and diagnostic approaches.
  • The device's small size and multi-functionality make it suitable for diverse biomedical applications.