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Published on: November 11, 2022
Chemical constituents of the stems of Celastrus rugosus
Ruijie Chang1, Chunhui Wang, Qi Zeng
1School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
Abstract:
Two new sesquiterpene pyridine alkaloids rugosusines A and B (1 and 2), and thirty-one known compounds were isolated from the stems of Celastrus rugosus. The structures of new compounds were elucidated by detailed spectroscopic analysis, including HR-ESI-MS and 2D NMR spectroscopic data. All the compounds were isolated from this plant for the first time. The cytotoxicities of these compounds were tested against SKOV3 and MGC-803 cell lines by CCK-8 method.
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