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Updated: May 11, 2026

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry (UPLC-HRMS)
Published on: May 20, 2013
[Mass spectrum characterization of five valepotriates by electrospray ionization tandem mass spectrometry]
Chun-Guo Wang1, Yong Liu, Jin-Li Shi
1Beijing University of Chinese Medicine, Beijing 100029, China.
Objective:
To discuss mass spectrum characterization of five valepotriates including 'monoene' type (didrovaltrate), 'diene' type (valtrate, acevaltrate) and 'four-olefinic' type (baldrinal and homobaldrinal) by electrospray ionization tandem mass spectrometry (ESI-MS(n)).
Method:
This study was carried out on the basis of electrospray ionization tandem mass spectrometric method and analysis of multistage fragments.
Result:
The fragmentation patterns and structural assignment of 'monoene' type, 'diene' type and 'four-olefinic' type valepotriates in ESI-MSn under positive mode were summarized.
Conclusion:
The compounds have a strong pyrolysis rules and it can provide reference date for valepotriates in rapid structural identification, quantitative analysis and pharmacokinetic study.
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