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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 11, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

[Changes in corneal thickness in glaucoma].

C Stefan, Adina Pop, Corina Avram

    Oftalmologia (Bucharest, Romania : 1990)
    |May 30, 2013
    PubMed
    Summary
    This summary is machine-generated.

    This study investigated how common glaucoma medications, including prostaglandin analogues, beta blockers, and carbonic anhydrase inhibitors, affect central corneal thickness. The findings provide insights into the ocular side effects of these glaucoma treatments.

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    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

    Published on: July 24, 2020

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    Last Updated: May 11, 2026

    Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
    07:51

    Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

    Published on: October 21, 2022

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
    07:44

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

    Published on: July 24, 2020

    Area of Science:

    • Ophthalmology
    • Clinical Pharmacology

    Background:

    • Glaucoma is a leading cause of irreversible blindness worldwide.
    • Effective management of intraocular pressure is crucial in glaucoma treatment.
    • Corneal thickness can influence intraocular pressure measurements and ocular health.

    Purpose of the Study:

    • To evaluate the impact of frequently used glaucoma medications on central corneal thickness.
    • To assess potential changes in corneal physiology due to prostaglandin analogues, beta blockers, and carbonic anhydrase inhibitors.

    Main Methods:

    • A retrospective, randomized clinical study was conducted.
    • Data from 46 eyes treated with glaucoma medications were analyzed.
    • Central corneal thickness was the primary outcome measure.

    Main Results:

    • Analysis revealed specific effects of prostaglandin analogues, beta blockers, and carbonic anhydrase inhibitors on central corneal thickness.
    • The study quantifies these changes, providing objective data on drug-induced corneal alterations.

    Conclusions:

    • Glaucoma medications can induce measurable changes in central corneal thickness.
    • Understanding these effects is important for accurate diagnosis and treatment monitoring in glaucoma patients.