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Updated: May 11, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Sutureless aortic valve replacement using perceval s valve.

Shahzad G Raja1

  • 1Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom. drrajashahzad@hotmail.com

Recent Patents on Cardiovascular Drug Discovery
|May 30, 2013
PubMed
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Sutureless aortic valve replacement offers a faster implantation time, potentially improving outcomes for high-risk patients with severe aortic stenosis. This technology reduces risks associated with longer surgeries.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • Severe symptomatic aortic valve stenosis necessitates surgical aortic valve replacement (SAVR) for optimal outcomes.
  • Increasing numbers of high-risk patients are referred for SAVR, posing significant surgical challenges.
  • Shorter cardiopulmonary bypass and cross-clamp times are crucial for mitigating surgical risk in these patients.

Purpose of the Study:

  • To review the published literature on the sutureless PERCEVAL S valve.
  • To evaluate the role of sutureless aortic valve replacement in managing critical aortic valve stenosis, particularly in high-risk individuals.

Main Methods:

  • Review of published clinical data and literature concerning the PERCEVAL S sutureless bioprosthetic valve.
  • Analysis of implantation techniques, clinical outcomes, and valve-related complications.

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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Published on: December 11, 2017

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Last Updated: May 11, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Main Results:

  • Sutureless valves, like PERCEVAL S, are not hand-sewn, reducing implantation time compared to conventional SAVR.
  • This technological advancement has the potential to improve outcomes for high-risk patients undergoing SAVR.
  • The PERCEVAL S valve has the largest published experience among available sutureless bioprostheses.

Conclusions:

  • Sutureless aortic valve technology offers a promising alternative for reducing surgical time in SAVR.
  • The PERCEVAL S valve demonstrates significant clinical experience and potential benefits for high-risk patients with aortic stenosis.