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Updated: May 11, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
Platelet transfusion therapy
Perumal Thiagarajan1, Vahid Afshar-Kharghan
1Department of Pathology, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX 77030, USA. perumalt@bcm.edu
Abstract:
Platelet transfusion therapy has become an integral part of the treatment of patients with hematological and solid tumor malignancy receiving chemotherapy. Since its introduction almost 60 years ago, several advances and refinements have been introduced in the collection, storage, and administration to improve the safety and efficacy of platelet transfusion. This review summarizes the current practice and clinical approach to patients with thrombocytopenia. Existing evidence-based guidelines for appropriate platelet transfusion is reviewed.
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