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Related Concept Videos

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...

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Related Experiment Video

Updated: May 11, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Peripheral primitive neuroectodermal tumour in a dog.

J Junginger1, A Röthlisberger, A Lehmbecker

  • 1Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg 17, D-30559 Hannover, Germany.

Journal of Comparative Pathology
|May 30, 2013
PubMed
Summary
This summary is machine-generated.

A rare peripheral primitive neuroectodermal tumor caused progressive paralysis in a German shepherd. Diagnosis involved advanced imaging and immunohistochemistry, identifying a neural origin. This case highlights a unique spinal tumor in canine neurology.

Area of Science:

  • Veterinary Neurology
  • Canine Oncology
  • Neuro-oncology

Background:

  • Peripheral primitive neuroectodermal tumors (PNETs) are rare embryonal tumors of neural origin.
Keywords:
dogimmunohistochemistryperipheral primitive neuroectodermal tumourspinal cord

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  • Spinal tumors in dogs can cause significant neurological deficits, including paraparesis and paraplegia.
  • Accurate diagnosis of spinal masses is crucial for appropriate treatment and prognosis.