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Updated: May 11, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer
Published on: January 5, 2024
Thrombosis and cancer: emerging data for the practicing oncologist
Gary H Lyman1, Alok A Khorana, Anna Falanga
1From the Duke University and the Duke Cancer Institute, Durham, NC; Department of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Immunohematology Division, Hospital Papa Giovanni XXIII, Bergamo, Italy.
The American Society of Clinical Oncology updated guidelines for cancer patients experiencing venous thromboembolism (VTE). Despite advances, managing VTE in cancer patients remains challenging due to increased risks and complex factors.
Area of Science:
- Oncology
- Hematology
Background:
- Venous thromboembolism (VTE) is a significant concern in cancer patients.
- The risk of VTE in cancer patients is increasing and multifactorial.
- Existing clinical practice guidelines require updates to address new evidence.
Purpose of the Study:
- To summarize the updated clinical practice guidelines from the American Society of Clinical Oncology (ASCO) for VTE in cancer patients.
- To highlight the persistent challenges in managing VTE in this population.
Main Methods:
- Review of recent studies and clinical evidence.
- Development of updated treatment and prevention strategies.
- Guideline formulation by expert consensus.
Main Results:
- ASCO has released updated guidelines for VTE management in cancer.
- VTE risk is linked to patient, disease, and treatment factors.
- Standard VTE treatment is generally applicable, but challenges persist.
Conclusions:
- Cancer-associated VTE requires careful management due to elevated risks.
- Providers face challenges managing VTE recurrence and mortality in cancer patients.
- Adherence to updated guidelines is crucial for optimal patient care.
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