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Related Experiment Videos

[Cordocentesis: experience in 391 initial samples].

C Donner1, P Simon, F Gosselin

  • 1Laboratoire de Cytogénétique, Hôpital Universitaire Brugmann.

Revue Medicale De Bruxelles
|June 1, 1990
PubMed
Summary
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Diagnostic cordocentesis, a fetal blood sampling technique, is safe and reliable for pregnancy management. This study reports on 391 procedures, confirming its utility in diagnosing fetal conditions.

Area of Science:

  • Perinatology
  • Fetal Medicine
  • Medical Diagnostics

Context:

  • Cordocentesis, a prenatal diagnostic procedure, involves sampling fetal blood from the umbilical cord.
  • This study analyzes a 4-year experience with diagnostic cordocentesis performed between gestational weeks 14 and 42.
  • The procedure is indicated for various fetal assessments, including infection risk, karyotyping, hemopathy, paternity testing, acid-base status, and biochemical analysis.

Purpose:

  • To evaluate the safety and reliability of diagnostic cordocentesis.
  • To report outcomes and complications associated with the procedure.
  • To provide data supporting the use of cordocentesis in pregnancy management.

Summary:

  • A total of 391 diagnostic cordocentesis procedures were performed on 360 patients.

Related Experiment Videos

  • The success rate for the first attempt was 90%, with a 4.1% fetal loss rate within one week post-procedure.
  • Complications included transient fetal bradycardia (9.9%) and bleeding (19%), with one fetal death possibly linked to the puncture.

    • Impact:

    • Cordocentesis is confirmed as a safe and dependable diagnostic tool in prenatal care.
    • The findings offer valuable insights for obstetricians regarding the procedural risks and benefits.
    • This data aids in informed decision-making for managing pregnancies requiring fetal diagnostic evaluation.