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Related Concept Videos

Gain01:15

Gain

Gain and phase shift are properties of linear circuits that describe the effect a circuit has on a sinusoidal input voltage or current. The circuit's behavior that contains reactive elements will depend on the frequency of the input sinusoid. As a result, it is observed that the gain and phase shift will all be frequency functions.
Gain:
Suppose Vin is the input and Vout is the output signal to a circuit.
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

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Related Experiment Video

Updated: May 11, 2026

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

Improved psychophysical methods to estimate peripheral gain and compression.

Ifat Yasin1, Vit Drga, Christopher J Plack

  • 1Ear Institute, University College London, London, UK. i.yasin@ucl.ac.uk

Advances in Experimental Medicine and Biology
|May 30, 2013
PubMed
Summary
This summary is machine-generated.

New methods for measuring hearing function, like the fixed-duration masking curve (FDMC), avoid biases from the medial olivocochlear reflex (MOCR). This allows for more accurate estimates of basilar membrane gain and compression.

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Last Updated: May 11, 2026

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Published on: January 29, 2014

Area of Science:

  • Auditory neuroscience
  • Psychoacoustics
  • Human physiology

Background:

  • Previous estimates of basilar membrane gain and compression may be influenced by the medial olivocochlear reflex (MOCR).
  • Longer masker durations in temporal masking curve (TMC) and additivity of forward masking (AFM) methods might inadvertently activate the MOCR.

Purpose of the Study:

  • To compare the fixed-duration masking curve (FDMC) method with existing TMC and AFM methods.
  • To investigate the impact of efferent pathway activation on estimates of auditory gain and compression using the FDMC method.

Main Methods:

  • Experiment 1: Compared TMC, AFM, and FDMC (25 ms stimulus duration) for estimating gain and compression.
  • Experiment 2: Utilized the FDMC method with a precursor sound to manipulate efferent activation and assess its effect on gain and compression.

Main Results:

  • Estimates of compression were similar across TMC, FDMC, and AFM methods.
  • Gain estimates were comparable between TMC and FDMC methods.
  • FDMC identified maximum compression at a lower input masker level than TMC.
  • Estimated gain decreased with increasing precursor level and increased with longer silent intervals, indicating efferent response decay.

Conclusions:

  • The FDMC method provides reliable estimates of auditory compression and gain, potentially unaffected by MOCR.
  • Auditory gain is modulated by efferent activity, with effects decaying over time.