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Updated: May 11, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
R3D Align web server for global nucleotide to nucleotide alignments of RNA 3D structures
Ryan R Rahrig1, Anton I Petrov, Neocles B Leontis
1Department of Mathematics and Statistics, Ohio Northern University, Ada, OH 45810, USA. r-rahrig@onu.edu
Abstract:
The R3D Align web server provides online access to 'RNA 3D Align' (R3D Align), a method for producing accurate nucleotide-level structural alignments of RNA 3D structures. The web server provides a streamlined and intuitive interface, input data validation and output that is more extensive and easier to read and interpret than related servers. The R3D Align web server offers a unique Gallery of Featured Alignments, providing immediate access to pre-computed alignments of large RNA 3D structures, including all ribosomal RNAs, as well as guidance on effective use of the server and interpretation of the output. By accessing the non-redundant lists of RNA 3D structures provided by the Bowling Green State University RNA group, R3D Align connects users to structure files in the same equivalence class and the best-modeled representative structure from each group. The R3D Align web server is freely accessible at http://rna.bgsu.edu/r3dalign/.
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