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[Phlebographic follow-up of successful fibrinolytically-treated deep thrombophlebitis]
B Eickerling1, H Rakus, M Martin
1Geriatrische Klinik, Städtischen Kliniken Duisburg.
Insights
Long-term results show fibrinolytic treatment for deep vein thrombosis has a low reocclusion rate. This suggests fibrinolysis is a viable treatment option for venous occlusions.
Area of Science:
- Vascular Surgery
- Thrombolytic Therapy
Context:
- Deep venous occlusions (DVO) pose significant health risks.
- Fibrinolytic therapy offers a potential treatment for DVO.
- Evaluating long-term outcomes of fibrinolysis is crucial for clinical practice.
Purpose:
- To assess the long-term efficacy and safety of fibrinolytic treatment for deep venous occlusions.
- To determine the reocclusion rates in patients treated with an ultrahigh streptokinase regimen.
Summary:
- This study evaluated 27 patients with deep venous occlusions treated with fibrinolysis.
- Follow-up averaged 18.9 months. Reocclusion rates were 9.5% for femoral vein thrombosis and 0% for iliac vein thrombosis.
- One case of late thrombus lysis was observed.
Impact:
- Fibrinolytic treatment demonstrates a low tendency for venous reocclusion after successful thrombolysis.
- These findings support fibrinolysis as an effective therapeutic strategy for deep vein thrombosis.
- The study encourages further consideration of fibrinolytic therapy in managing venous thromboembolic disease.
Abstract:
The present study deals with long-term results in patients in whom deep venous occlusions were removed by fibrinolytic treatment. For this an ultrahigh streptokinase regimen was used. The average follow-up period was 18.9 +/- 6.7 months. The number of patients investigated was 27. In the group of femoral veins formerly cleared by fibrinolysis 2 of 21 (9.5%) were recorded as reoccluded. An unexpected removal of a femoral thrombosis still in existence immediately after fibrinolytic therapy was seen in one patient and evaluated as a late lytic event. In the group of iliac vein thrombosis cleared by fibrinolytic treatment no reocclusions occurred. In conclusion it can be said that the reocclusion-tendency of veins cleared by fibrinolysis is relatively low. This finding constitutes a special incentive for fibrinolytic treatment of deep vein thrombosis.