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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Endoscopic Studies II: Thoracocentesis

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Related Experiment Video

Updated: May 11, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

Image-guided pleural biopsy.

Coenraad F N Koegelenberg1, Andreas H Diacon

  • 1Division of Pulmonology, Department of Medicine, Stellenbosch University, Tygerberg Academic Hospital, Cape Town, South Africa. coeniefn@sun.ac.za

Current Opinion in Pulmonary Medicine
|May 31, 2013
PubMed
Summary
This summary is machine-generated.

Image-guided pleural biopsy, combined with repeat thoracocentesis, offers a safe and effective method for diagnosing pleural exudates. This approach enhances diagnostic yield, particularly for malignant pleural disease, proving more cost-effective than other methods.

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Last Updated: May 11, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
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Published on: November 10, 2023

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
04:10

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies

Published on: July 19, 2024

Area of Science:

  • Pulmonology
  • Radiology
  • Thoracic Surgery

Background:

  • Diagnostic uncertainty persists for pleural exudates not diagnosed by initial thoracocentesis.
  • Both closed pleural biopsy and thoracoscopy are options for pleural tissue acquisition.
  • Image guidance for closed pleural biopsy is an evolving area.

Purpose of the Study:

  • To review developments in image-guided closed pleural biopsy.
  • To evaluate the efficacy and safety of image-guided pleural biopsy for undiagnosed pleural exudates.

Main Methods:

  • Review of recent studies on computed tomography (CT) and ultrasound-guided closed pleural biopsy.
  • Analysis of imaging's role in targeting pleural abnormalities and improving biopsy yield.
  • Assessment of image-guided repeat thoracocentesis and biopsy in conjunction.

Main Results:

  • CT and ultrasound guidance enhance the yield and safety of closed pleural biopsy.
  • Imaging improves targeting of malignant pleural disease and reduces false-negative rates.
  • Image-guided procedures approach thoracoscopy yields, especially for thickened or nodular pleura.

Conclusions:

  • Image-guided pleural biopsy with repeat thoracocentesis is safe, inexpensive, accessible, and sensitive.
  • This method provides further examination for patients with undiagnosed pleural exudates.
  • It represents an efficient alternative to more invasive procedures.