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Related Experiment Video

Updated: May 11, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
04:00

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Corneal sensitivity may decrease in adenoviral epidemic keratoconjunctivitis--a confocal microscopic study.

Hilal Eser Ozturk1, Baris Sonmez, Umit Beden

  • 1Samsun Education and Research Hospital, Samsun, Turkey. hilaleser@yahoo.com

Eye & Contact Lens
|May 31, 2013
PubMed
Summary

A new clinical finding of decreased corneal sensitivity was observed in epidemic keratoconjunctivitis. Confocal microscopy helped evaluate these transient changes in corneal nerves and inflammation.

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Area of Science:

  • Ophthalmology
  • Virology
  • Microscopy

Background:

  • Epidemic keratoconjunctivitis (EKC) is a viral eye infection.
  • Corneal involvement is a common complication of EKC.

Purpose of the Study:

  • To identify and characterize decreased corneal sensitivity in EKC.
  • To utilize corneal confocal microscopy to assess associated microstructural changes.

Main Methods:

  • Study included 41 eyes from 28 patients with corneal infiltrates due to EKC.
  • Corneal sensitivity was measured, and confocal microscopy was performed.

Main Results:

  • Decreased corneal sensitivity was found in 74.3% of affected eyes.
  • Confocal microscopy revealed epithelial cell changes, inflammatory infiltrates, and altered corneal stroma and nerves.

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Last Updated: May 11, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
04:00

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Published on: August 2, 2024

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
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Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

  • Corneal sensitivity normalized within a mean of 8.5 days.

    • Conclusions:

    • Transient decreased corneal sensitivity is a potential clinical sign in EKC.
    • Confocal microscopy is valuable for evaluating corneal changes during EKC.
    • Further research is needed to elucidate the exact nature of this finding.