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Rheumatoid arthritis and hypercoagulable state.

R E Smith¹, A L Theisen

¹Department of Medicine, Medical College of Wisconsin, Milwaukee.

The American Journal of the Medical Sciences

|July 1, 1990

Summary

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Rheumatoid arthritis is not typically linked to recurrent thrombosis. This case study details a patient experiencing life-threatening blood clots while on anticoagulants, who later developed severe rheumatoid arthritis.

Area of Science:

Rheumatology
Hematology
Internal Medicine

Background:

Rheumatoid arthritis (RA) is an autoimmune disease primarily affecting joints.
Recurrent thrombosis is not a commonly recognized complication of rheumatoid arthritis.

Observation:

A patient presented with recurrent, life-threatening thrombotic events.
The patient was undergoing anticoagulant therapy during these episodes.
Subsequently, the patient developed severe rheumatoid arthritis.

Findings:

Successful treatment of rheumatoid arthritis with antiarthritic therapy coincided with the cessation of thrombotic episodes.
Withdrawal of anticoagulant medication was also a factor in the resolution of thrombosis.

Implications:

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This case suggests a potential, albeit unusual, link between rheumatoid arthritis and recurrent thrombosis.
Further research may be warranted to explore the underlying mechanisms connecting these conditions.
Management of thrombosis in RA patients may require a multidisciplinary approach considering both conditions.