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Updated: May 11, 2026

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR (RS-PCR)

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR (RS-PCR)

Published on: November 4, 2016

Methicillin-resistant Staphylococcus aureus risk profiling: who are we missing?

Janet Pasricha¹, Stephan Harbarth, Thibaud Koessler

¹Infection Control Program, University of Geneva Hospitals and Faculty of Medicine, 4 Rue Gabrielle Perret-Gentil, Geneva 1211, Switzerland. stephan.harbarth@hcuge.ch.

Antimicrobial Resistance and Infection Control

|June 1, 2013

Summary

A significant number of patients missed MRSA screening, particularly younger individuals, those transferred from other wards, and cancer patients. Understanding these missed cases is crucial for improving methicillin-resistant Staphylococcus aureus (MRSA) prediction tools.

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Last Updated: May 11, 2026

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR (RS-PCR)

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR (RS-PCR)

Published on: November 4, 2016

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Area of Science:

Infectious Diseases
Epidemiology
Healthcare Management

Background:

Targeted screening for methicillin-resistant Staphylococcus aureus (MRSA) carriage is key for MRSA control.
Prediction tools are used to identify high-risk patients for screening.
Previous studies noted many eligible patients were not screened, but their characteristics were often undescribed.

Purpose of the Study:

To determine the rate and characteristics of patients missed by an MRSA screening program.
To assess the potential impact of missed patients on the accuracy of clinical prediction tools.

Main Methods:

Prospective screening of all patients admitted to 13 internal medicine wards at the University of Geneva Hospital (HUG) from March-June 2010.
Analysis of patient demographics and transfer status for those not screened.
Multivariate regression to identify characteristics associated with missed screening.

Main Results:

13.6% (267/1968) of admitted patients failed to undergo MRSA screening.
Younger patients (<50 years), those transferred from other wards, and patients with a history of malignancy were more likely to be missed.
No significant difference in previous MRSA carriage rates between screened and unscreened groups.

Conclusions:

Patients missed by MRSA screening programs may introduce bias into risk prediction scores.
Reporting on the characteristics of missed patients is essential for accurate interpretation of MRSA prediction tools.