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Updated: May 11, 2026

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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
DISSECT: a new mnemonic-based approach to the categorization of aortic dissection
M D Dake1, M Thompson, M van Sambeek
1Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA. mddake@stanford.edu
Summary
A new classification system, DISSECT, aids in managing aortic dissection by assessing six key features. This system improves therapeutic decision-making, especially with the rise of endovascular techniques for aortic dissection.
Area of Science:
- Cardiovascular Surgery
- Vascular Medicine
- Medical Imaging
Background:
- Traditional aortic dissection classification systems (e.g., DeBakey, Stanford) are increasingly inadequate due to the evolving landscape of endovascular interventions.
- The DEFINE Project's Working Group on Aortic Diseases recognized the need for a contemporary system reflecting current therapeutic options.
- Aortic dissection remains a complex and catastrophic vascular emergency requiring precise management strategies.
Purpose of the Study:
- To develop and introduce the DISSECT classification system for aortic dissection.
- To provide a framework that incorporates features crucial for contemporary treatment decisions, including endovascular approaches.
- To enhance clinical communication and guide therapeutic selection for aortic dissection.
Main Methods:
- The DISSECT classification is a mnemonic-based system evaluating six critical characteristics of aortic dissection.
- Key features assessed include: duration of disease, intimal tear location, aortic size, segmental extent, clinical complications, and thrombus presence.
- This approach contrasts with older systems by including factors relevant to endovascular procedures.
Main Results:
- The DISSECT system facilitates a comprehensive assessment of aortic dissection relevant to modern therapeutic options.
- It highlights specific features influencing the choice between medical management, open surgery, or endovascular repair.
- The system addresses limitations of historical classifications in the context of advanced interventional techniques.
Conclusions:
- The DISSECT classification system offers a valuable tool for contemporary aortic dissection management, particularly for type B dissections amenable to endovascular therapy.
- While not directly used for type A aortic dissection repair, it can guide adjunctive interventions for associated complications.
- DISSECT aims to improve decision-making by providing a structured analysis of disease features, moving beyond outdated categorization schemes.

