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Cryptorchidism as a potential source of misinterpretation in ¹⁸FDG-PET imaging in restaging lymphoma patients
David Groheux1, Pierre Teyton, Laetitia Vercellino
1Department of Nuclear Medicine, Saint-Louis Hospital, Paris, France.
Purpose:
The estimated prevalence of cryptorchidism in young males is close to 2%. In oncological PET/CT studies, it might be difficult to recognize false-positive ¹⁸FDG uptake due to an ectopic testis.
Materials And Methods:
In this pilot study, we report on three patients with lymphoma referred for assessment of response to treatment and in whom cryptorchidism was not known at the time of ¹⁸FDG-PET/CT imaging.
Results:
In each of these patients, moderate ¹⁸FDG uptake corresponding to an ovoid mass in the inguinal canal was (or could has been) misinterpreted as a lymphoma-involved inguinal lymph node. Clues to avoid misinterpretation are discussed.
Conclusion:
Moderate ¹⁸FDG uptake in ectopic testes represents a potential source of false-positive at initial staging or evaluation of therapeutic response of lymphomas and other malignancies that needs to be recognized.
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