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Updated: May 11, 2026
MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
The synthesis of neurotensin antagonist SR 48692 for prostate cancer research
I R Baxendale1, S Cheung, M O Kitching
1Department of Chemistry, Durham University, South Road, Durham DH1 3LE, United Kingdom. i.r.baxendale@durham.ac.uk
Abstract:
An improved synthesis of the molecule SR 48692 is presented and its use as a neurotensin antagonist biological probe for use in cancer research is described. The preparation includes an number of enhanced chemical conversions and strategies to overcome some of the limiting synthetic transformations in the original chemical route.
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