Baboon syndrome induced by hydroxyzine
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Published on: January 15, 2010
Hayet Akkari1, Hichem Belhadjali, Monia Youssef
1Department of Dermatology, Fattouma Bourguiba Hospital, Monastir, Tunisia.
Abstract:
Hydroxyzine-induced drug eruptions are very rare. We report here a typical case of drug-related Baboon syndrome or symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) which was induced by hydroxyzine in a 60-year-old man. The diagnosis was confirmed by positive patch and oral accidental provocation tests with hydroxyzine. Patch tests and oral provocation tests with cetirizine and levocetirizine were negative. A review of the literature identified only 17 reported cases of hydroxyzine-induced drug eruptions. To the best of our knowledge, we report here the first case of hydroxyzine-induced SDRIFE.
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