Related Experiment Video
Updated: May 10, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4-Methyl-anilinium 4-hy-droxy-benzene-sulfonate
1PG and Research Department of Physics, Queen Mary's College, Chennai-4, Tamilnadu, India.
Abstract:
In the crystal of the title molecular salt, C7H10N(+)·C6H5O4S(-), the benzene-sulfonate units are linked through phenol-sulfonate O-H⋯O hydrogen bonds, forming chains along the c-axis direction. These chains are linked via N-H⋯O hydrogen bonds involving two of the three H atoms of the ammonium group of the 4-methyl-anilium cation, giving rise to two-dimensional networks parallel to the bc plane which are further connected through an additional N-H⋯O inter-action in which the third ammonium H atom is involved, generating a three-dimensional network.
Related Concept Videos
Electrophilic Aromatic Substitution: Sulfonation of Benzene
Amines to Sulfonamides: The Hinsberg Test
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing sulfonyl...
Diazonium Group Substitution: –OH and –H
Determining the pH of Salt Solutions
Acidity of 1-Alkynes
The acidic strength of hydrocarbons follows the order: Alkynes > Alkenes > Alkanes. The strength of an acid is commonly expressed in units of pKa — the lower the pKa, the stronger the acid. Among the hydrocarbons, terminal alkynes have lower pKa values and are, therefore, more acidic. For example, the pKa values for ethane, ethene, and acetylene are 51, 44, and 25, respectively, as shown here.
Electrophilic Aromatic Substitution: Nitration of Benzene

