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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Isopropyl 3-phenyl-isoxazole-5-carboxyl-ate
Li Wang1, Xue-Ying Liu, Zheng-Wei Li
1Department of Chemistry, School of Preclinical Medicine, Shanxi Medical University, 56 Xinjian South Road, 030001 Tai Yuan, People's Republic of China ; Affiliated Hospital of Xi'an Medical College, 48 Fenggao West Road, 710077 Xi-An, People's Republic of China.
Abstract:
In the title compound, C13H13NO3, the isoxazole ring is approximately coplanar with the phenyl ring, the dihedral angle between their planes being 7.37 (19)°. In the crystal, centrosymmetrically related mol-ecules are linked into dimers by pairs of C-H⋯O hydrogen bonds, generating a ring of graph-set motif R 2 (2)(10).
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