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Qulaity of life in cystic fibrosis children

Hamid-Reza Kianifar1, Banafsheh Bakhshoodeh, Paria Hebrani

  • 1Allergy Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Iranian Journal of Pediatrics
|June 1, 2013
PubMed

Insights

Quality of life (QoL) is significantly lower in children and adolescents with cystic fibrosis (CF) compared to healthy peers. These findings highlight the need to integrate QoL assessments into CF care.

Area of Science:

  • Pediatric Health
  • Genetic Disorders
  • Quality of Life Research

Background:

  • Cystic fibrosis (CF) is a chronic, multisystem genetic disease with variable clinical severity.
  • Assessing quality of life (QoL) in CF patients provides crucial insights into the disease's impact.
  • Understanding QoL differences is essential for comprehensive patient care.

Purpose of the Study:

  • To evaluate the quality of life (QoL) in children and adolescents diagnosed with cystic fibrosis (CF).
  • To compare the QoL of CF patients with a control group of healthy individuals.
  • To identify specific domains of QoL affected by CF in pediatric populations.

Main Methods:

  • Study included pediatric patients aged 2-18 years with a confirmed diagnosis of cystic fibrosis.
  • Quality of life (QoL) was assessed in CF patients.
  • QoL data from CF patients were compared against a matched control group.

Main Results:

  • Children's self-reports indicated significant differences in emotional, physical, social, and school performance scores between CF patients and controls (P<0.05).
  • Parents' reports revealed decreased QoL scores for CF patients in physical, social, and overall domains (P<0.05).
  • Both patient and parent perspectives underscore a diminished QoL associated with cystic fibrosis.

Conclusions:

  • Quality of life (QoL) in pediatric and adolescent patients with cystic fibrosis (CF) appears to be significantly impaired.
  • Therapeutic strategies for CF should incorporate assessments and interventions addressing perceived QoL.
  • Addressing QoL is a critical component of holistic CF management.
Abstract

Keywords:
AdolescenceChildCystic fibrosisQuality of life

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