Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Collision Sports: The Need for Further Education in Rugby.

Cureus·2026
Same author

Mesenchymal Stem Cell Therapy for Neurological Complications of Prematurity: A Narrative Review.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Homer, Hippocrates, and modern military warfare: The helmet dilemma continues.

Medical journal, Armed Forces India·2026
Same author

Presumptive mivacurium chloride-associated histamine release resulting in overt tissue edema during endoscopic thyroidectomy: a report of two cases.

BMC anesthesiology·2026
Same author

Women's Health in Rugby: It Is More Than Orthopedics.

Cureus·2026
Same author

Stroke Rehabilitation, Novel Technology and the Internet of Medical Things.

Brain sciences·2026
Same journal

Circulating metabolome as key biomarkers for ventilator-associated pneumonia: Case-Control study in a tertiary care hospital of North India.

International journal of critical illness and injury science·2026
Same journal

Toward an "accordion intensive care unit" model: A flexible, patient-centered approach to critical-care capacity.

International journal of critical illness and injury science·2026
Same journal

Evaluating the diagnostic utility of heart-type fatty acid-binding protein as a novel biomarker for acute coronary syndrome in the emergency department: A 1-year cross-sectional study.

International journal of critical illness and injury science·2026
Same journal

Prognostic accuracy of mid-regional proadrenomedullin in patients with sepsis - A longitudinal observational study.

International journal of critical illness and injury science·2026
Same journal

Back to basics in critical care: Can hematological ratios refine sepsis risk stratification?

International journal of critical illness and injury science·2026
Same journal

Evaluating the role of high-dose intravenous thiamine supplementation for lactate clearance in patients with cirrhosis and sepsis.

International journal of critical illness and injury science·2026
See all related articles

Related Experiment Video

Updated: May 10, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Amniotic fluid embolism.

Cattleya Thongrong1, Pornthep Kasemsiri, James P Hofmann

  • 1Department of Anesthesiology, Division of Trauma, Critical Care and Burn, The Ohio State University College of Medicine, Columbus, USA ; Department of Anesthesiology, Srinagarind Hospital, Faculty of Medicine at the Khon Kaen University, Khon Kaen, Thailand.

International Journal of Critical Illness and Injury Science
|June 1, 2013
PubMed
Summary
This summary is machine-generated.

Amniotic fluid embolism (AFE) is a rare but devastating pregnancy complication. Early recognition and aggressive supportive care are crucial for improving outcomes and reducing mortality in patients experiencing AFE.

Keywords:
Amniotic fluid embolismdiagnosisfocused summarymanagement

More Related Videos

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
05:40

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Related Experiment Videos

Last Updated: May 10, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
05:40

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Area of Science:

  • Obstetrics and Gynecology
  • Critical Care Medicine
  • Perinatal Medicine

Background:

  • Amniotic fluid embolism (AFE) is a rare, unpredictable, and unpreventable obstetric emergency.
  • Despite low incidence, AFE carries a high risk of severe maternal and infant morbidity and mortality.

Purpose of the Study:

  • To review the current medical knowledge on amniotic fluid embolism.
  • To outline incidence, risk factors, diagnosis, pathophysiology, and clinical manifestations of AFE.
  • To emphasize the importance of modern aggressive supportive care in managing AFE.

Main Methods:

  • This is a review article.
  • It synthesizes current medical literature on amniotic fluid embolism.
  • Focuses on diagnostic and management strategies.

Main Results:

  • AFE can lead to cardiac arrest, ARDS, coagulopathy, encephalopathy, seizures, and death.
  • Modern aggressive supportive care has reduced the high mortality rate associated with AFE.
  • Vigilance, clinical suspicion, and rapid resuscitation are key to successful management.

Conclusions:

  • Amniotic fluid embolism remains a critical obstetric complication requiring immediate and comprehensive care.
  • Effective management hinges on prompt recognition and aggressive resuscitative efforts.
  • Continued research and clinical vigilance are essential for improving patient outcomes in AFE.