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Updated: May 10, 2026

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Practical biometric ratios of first-trimester screening.

R N Ergin1, M Yayla, A S Ergin

  • 1Bayindir Icerenköy Hospital, Department of Gynecology and Obstetrics, Istanbul, Turkey. drnidaergin@gmail.com

Clinical and Experimental Obstetrics & Gynecology
|June 4, 2013
PubMed
Summary

This study identifies key fetal biometry ratios for accurate first-trimester screening. Crown rump length to biparietal diameter (CRL/BPD) and abdominal circumference to biparietal diameter (AC/BPD) ratios are most practical for clinical use.

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Area of Science:

  • Maternal-fetal medicine
  • Prenatal diagnostics
  • Fetal ultrasonography

Background:

  • First-trimester screening is crucial for assessing fetal well-being and detecting anomalies.
  • Accurate biometric measurements are essential for reliable screening.
  • Established biometry ratios can enhance measurement accuracy and anomaly detection.

Purpose of the Study:

  • To determine practical fetal biometry ratios for first-trimester screening.
  • To improve the accuracy of fetal measurements during early pregnancy.
  • To aid in the recognition of abnormal or mistaken fetal measurements.

Main Methods:

  • Retrospective analysis of 1,615 singleton pregnancies undergoing first-trimester screening (2004-2010).
  • Exclusion of pregnancies with fetal anomalies, maternal systemic diseases, or familial genetic conditions.

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Last Updated: May 10, 2026

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  • Calculation and comparison of various fetal biometric ratios (e.g., CRL/BPD, AC/BPD, CRL/AC) at 11-13 weeks gestation.

    • Main Results:

    • Established mean and standard deviation values for multiple fetal biometry ratios.
    • Identified ratios with small standard deviations, indicating greater consistency: CRL/BPD, AC/BPD, CRL/AC, CRL/HC, and HC/AC.
    • Linear regression analysis derived equations for these ratios, with AC/BPD and CRL/AC showing particularly constant relationships.

    Conclusions:

    • The ratios of crown-rump length to biparietal diameter (CRL/BPD), abdominal circumference to biparietal diameter (AC/BPD), and crown-rump length to abdominal circumference (CRL/AC) are highly practical.
    • These selected ratios demonstrate utility in first-trimester fetal ultrasonography practice.
    • The findings support the use of specific biometry ratios for enhanced accuracy in early prenatal assessments.