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Updated: May 10, 2026

Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts
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[Strategy for keeping efficient expression and pharmacodynamics in reducing rAAV gene medicine immune response based

Guo-Hai Zhang1, Shu-Lan Zeng, Rui-An Xu

  • 1State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China.

Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|June 4, 2013
PubMed
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Reducing immune responses to adeno-associated virus (AAV) gene therapy is crucial. Strategies focus on optimizing AAV administration, vector design, and promoter selection to maintain efficacy while lowering vector dosage.

Area of Science:

  • Gene Therapy
  • Immunology
  • Molecular Biology

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