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Related Experiment Video

Updated: May 10, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Benign dermoscopic features in melanoma.

A Di Stefani¹, C Massone, H P Soyer

¹Department of Dermatology, University of Rome Tor Vergata, Rome, Italy; Department of Dermatology, Medical University of Graz, Graz, Austria.

Journal of the European Academy of Dermatology and Venereology : JEADV

|June 4, 2013

Summary

This summary is machine-generated.

Many melanomas display benign dermoscopic features (BDF), a common diagnostic pitfall. Awareness of these benign features in melanoma is crucial for accurate clinical diagnosis.

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Area of Science:

Dermatology
Dermoscopy
Oncology

Background:

Benign dermoscopic features (BDF) are typically associated with benign melanocytic lesions.
The presence and extent of BDF in melanoma require further investigation.

Purpose of the Study:

To determine the frequency and extension of benign dermoscopic features (BDF) in melanoma.
To analyze the correlation of BDF with melanoma characteristics and diagnostic accuracy.

Main Methods:

Retrospective review of 516 histopathologically proven melanomas.
Correlation of BDF with Breslow thickness, nevus association, and pre-operative diagnosis.

Main Results:

42% of melanomas exhibited BDF, with 12.3% showing BDF occupying over half the lesion.
Common BDF included pigment network, homogeneous pattern, and globules/cobblestone.
BDF were associated with thinner melanomas and more frequent in nevus-associated melanoma (67.1%) than melanoma de novo (35.7%).
Melanoma diagnosis was achieved in only 54.1% of cases with BDF.

Conclusions:

A significant proportion of melanomas can present with benign dermoscopic features.
Clinicians must recognize BDF in melanoma as a potential diagnostic challenge.