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Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

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Progress in developing common data elements for traumatic brain injury research: version two--the end of the

Ramona Hicks1, Joseph Giacino, Cynthia Harrison-Felix

  • 11 The National Institute of Neurological Disorders and Stroke , Bethesda, Maryland.

Journal of Neurotrauma
|June 4, 2013
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Summary

Updated traumatic brain injury (TBI) common data elements (CDEs) now support diverse research across all ages and injury severities. Version 2 offers a comprehensive data dictionary to enhance TBI research and data sharing.

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Area of Science:

  • Neuroscience
  • Public Health
  • Biomedical Informatics

Background:

  • Traumatic brain injury (TBI) research and data sharing are critical for advancing patient care.
  • Previous common data elements (CDEs) were limited to acute, adult, hospital-based TBI studies.
  • A need existed to expand TBI CDEs for broader applicability across diverse populations and injury phases.

Purpose of the Study:

  • To update and broaden the utility of traumatic brain injury (TBI) common data elements (CDEs).
  • To create a comprehensive data dictionary relevant for all ages, injury severities, and recovery phases.
  • To facilitate data sharing and meta-analysis in TBI research.

Main Methods:

  • Convened experts to update TBI CDE recommendations.
  • Organized the second version (v.2) of TBI CDEs around four major study types: epidemiological, acute hospitalized, rehabilitation, and mild TBI/concussion.
  • Identified core, basic, and supplemental CDEs based on study relevance.

Main Results:

  • The second version (v.2) of TBI CDEs includes approximately 900 elements.
  • CDEs were categorized into core (universally relevant), basic (group-specific), and supplemental (goal-dependent).
  • Significant overlap in CDEs across study types was identified, promoting cross-study comparisons and meta-analyses.

Conclusions:

  • Version 2 of TBI CDEs provides a robust data dictionary for diverse research applications.
  • The updated CDEs enhance the ability to share data and conduct comparative studies in TBI research.
  • Ongoing evaluation of CDE usefulness post-implementation is recommended for future modifications.