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Related Concept Videos

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...

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Related Experiment Video

Updated: May 10, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
06:16

mirMachine: A One-Stop Shop for Plant miRNA Annotation

Published on: May 1, 2021

PMTED: a plant microRNA target expression database.

Xiuli Sun1, Boquan Dong, Lingjie Yin

  • 1Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun 130012, China.

BMC Bioinformatics
|June 4, 2013
PubMed
Summary
This summary is machine-generated.

The Plant MiRNA Target Expression Database (PMTED) offers a centralized resource for analyzing microRNA (miRNA) target gene expression from microarray data. This tool aids researchers in understanding plant development and stress responses by providing accessible data and visualization tools.

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Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

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Related Experiment Videos

Last Updated: May 10, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
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Published on: May 1, 2021

A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
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Published on: January 21, 2020

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
08:40

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

Published on: April 6, 2012

Area of Science:

  • Plant biology
  • Genomics
  • Bioinformatics

Background:

  • MicroRNAs (miRNAs) regulate plant development and stress responses via target mRNA interactions.
  • Identifying miRNA targets is crucial but challenging due to scattered microarray data.
  • Existing data requires significant pre-processing and analytical tools for accessibility.

Purpose of the Study:

  • To develop a database for retrieving and analyzing plant miRNA target expression profiles.
  • To integrate and present scattered microarray data for easier researcher access.
  • To facilitate the study of miRNA functions and their target genes in plants.

Main Methods:

  • Developed the Plant MiRNA Target Expression Database (PMTED).
  • Integrated manually curated microarray data with miRNA target information.
  • Implemented query functions for miRNA/target sequences, gene ontology, and expression profiles.
  • Created a global meta-network visualization tool using Cytoscape Web.
  • Included a portal for novel miRNA target prediction and expression retrieval.

Main Results:

  • PMTED provides a comprehensive platform for accessing and analyzing plant miRNA target expression.
  • The database enables the construction and visualization of miRNA-target networks across species and conditions.
  • Facilitates the exploration of conserved and novel miRNA functions.

Conclusions:

  • PMTED leverages microarray data to reveal the contextual significance of miRNA targets.
  • The database aids functional investigations of both miRNAs and their targets in plants.
  • PMTED is freely available and will be continuously updated for non-commercial research use.