Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Problem-Solving

Problem-Solving

Effective problem-solving consists of two steps: 1. identifying the problem and 2. selecting the appropriate problem-solving strategy (i.e., a plan of action used to find a solution). Humans use four problem-solving strategies:

Bioreactor Controls-III

Bioreactor Controls-III

Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...

Cross-Sectional Research

Cross-Sectional Research

In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...

Creative Thinking

Creative Thinking

Creative thinking encompasses innovative and unconventional methods for addressing challenges, often leading to groundbreaking solutions. Instead of focusing solely on enhancing existing systems, such as increasing smartphone battery capacity, creative thinking might inspire advancements like energy-efficient batteries or processors that minimize power consumption. This multidimensional approach underscores the importance of exploring novel pathways to innovation.
Divergent thinking is the...

Coping Strategies: Problem Focused

Coping Strategies: Problem Focused

Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...

Frustration and Conflict: Approach-Approach, Approach-Avoidance

Frustration and Conflict: Approach-Approach, Approach-Avoidance

Frustration occurs when people are obstructed or prevented from achieving a desired goal or fulfilling a perceived need. For example, when someone's input is ignored in a discussion, it can lead to feelings of frustration. Conflict, however, arises from opposing interests, goals, or actions. Conflicts can take various forms based on the nature of these opposing desires or goals.
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable options,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dissociation of the nuclear basket triggers chromosome loss in aging yeast.

eLife·2025

Same author

A network of P-body and Whi3 condensates adjusts cell fate decisions to cellular context.

Molecular cell·2025

Same author

The Yin and Yang of replicative aging and rejuvenation.

Current opinion in genetics & development·2025

Same author

Global profiling of protein complex dynamics with an experimental library of protein interaction markers.

Nature biotechnology·2024

Same author

Correction: Fission-independent compartmentalization of mitochondria during budding yeast cell division.

The Journal of cell biology·2024

Same author

Microtubule specialization by +TIP networks: from mechanisms to functional implications.

Trends in biochemical sciences·2024

Search research articles

Related Experiment Video

Updated: May 10, 2026

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

New approaches to an age-old problem.

Lori Clay¹, Yves Barral

¹Institute of Biochemistry, Department of Biology, ETH Zurich, Schafmattstrasse 18, 8093 Zurich, Switzerland.

Current Opinion in Biotechnology

|June 4, 2013

Summary

This summary is machine-generated.

Ageing is universal, but its molecular basis is complex. Budding yeast (Saccharomyces cerevisiae) is a key model organism for studying ageing, with systems biology offering new insights into this fundamental biological process.

More Related Videos

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Published on: June 13, 2017

Related Experiment Videos

Last Updated: May 10, 2026

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Published on: June 13, 2017

Area of Science:

Gerontology
Molecular Biology
Systems Biology

Background:

Ageing is a universal biological process with complex molecular mechanisms that are challenging to study in humans.
The budding yeast Saccharomyces cerevisiae serves as a crucial model organism for ageing research due to its simplicity.
Systems biology approaches have become vital for understanding complex biological networks and pathways in ageing.

Purpose of the Study:

To review the current understanding of ageing in Saccharomyces cerevisiae.
To highlight recent high-throughput systems and systems biology approaches for ageing research in yeast.

Main Methods:

Review of existing literature on yeast ageing.
Discussion of systems biology and high-throughput methodologies applied to ageing research.

Main Results:

Yeast ageing research has advanced significantly, providing a simplified model for complex biological processes.
Systems biology enables mapping of regulatory networks and analysis of signal transduction pathways relevant to ageing.
High-throughput approaches offer novel strategies for deeper investigation into yeast ageing mechanisms.

Conclusions:

Saccharomyces cerevisiae is an invaluable model for deciphering the molecular intricacies of ageing.
Systems biology and high-throughput methods are powerful tools for accelerating discoveries in yeast ageing.
Further research utilizing these approaches will enhance our understanding of fundamental ageing processes.