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Synthesis of a Water-soluble Metal–Organic Complex Array
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Design, synthesis and biological evaluation of novel estrogen-derived steroid metal complexes

Xinlong Zhang1, Ziqing Zuo, Juan Tang

  • 1State Key Laboratory of Virology, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China.

Bioorganic & Medicinal Chemistry Letters
|June 4, 2013
PubMed

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Isomerism in Complexes
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Complexation Equilibria: The Chelate Effect

In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
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Metal-Ligand Bonds

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Structural Isomerism

Isomerism in Complexes
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