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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

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Cognitive vulnerability for depression in HIV.

Roger C McIntosh¹, Julia S Seay, Michael H Antoni

¹Department of Health Psychology, University of Miami, United States. rmcintosh@psy.miami.edu

Journal of Affective Disorders

|June 4, 2013

Summary

This summary is machine-generated.

Cognitive coping strategies impact depression in people with HIV by influencing automatic thoughts. Neurocognitive deficits in HIV can impair this process, affecting mood regulation.

Keywords:

Automatic thoughts Cognitive coping Dementia Depression HIV

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Area of Science:

Psychiatry
Neuroscience
Psychology

Background:

Depression is linked to biased cognitive processing, including automatic thoughts and mood regulation.
Adaptive coping strategies like acceptance and positive reframing are associated with lower depression in individuals with HIV.
The moderating role of HIV-related neurocognitive deficits in these cognitive-depression relationships is not well understood.

Purpose of the Study:

To investigate the mediating role of automatic thoughts (positive and negative) in the relationship between coping strategies and depressed affect.
To examine whether HIV-related neurocognitive deficits moderate the indirect effects of coping on depressive symptoms.

Main Methods:

Secondary analysis of data from a randomized trial involving HIV-positive adults.
Assessment of coping strategies, depressive symptoms, positive automatic thoughts (PAT), negative automatic thoughts (NAT), and neurocognitive function (HIV-dementia).

Main Results:

Cognitive coping was significantly related to depressed mood, mediated by both NAT and PAT.
The indirect effect of coping on depressive symptoms through automatic thoughts was moderated by neurocognitive function.

Conclusions:

The findings support a cognitive vulnerability model for depression in the context of HIV.
HIV-related neurocognitive deficits may hinder the effective use of coping strategies, impacting the regulation of automatic thoughts and mood.