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Related Experiment Video

Updated: May 10, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

The circadian system: plasticity at many levels.

N I Muraro¹, N Pírez, M F Ceriani

¹Laboratorio de Genética del Comportamiento, Fundación Instituto Leloir, IIB-BA-CONICET, Buenos Aires, Argentina.

|June 4, 2013

Summary

The circadian system shows remarkable plasticity, adapting physiology and behavior daily. This review explores structural changes and daily adjustments in clock outputs, highlighting the system's flexibility.

Keywords:

AVP BRP CRY CRYPTOCHROME DD DN LD LL LN LNds LPNs PDF PDH PER PERIOD SCN TIM TIMELESS VIP arginine vasopressin bruchpilot circadian network circadian plasticity clock neurons constant darkness constant light dorsal lateral neurons dorsal neuron lLNvs large ventral lateral neurons lateral neuron lateral posterior neurons light–dark pigment dispersing factor pigment dispersing hormone rhythmic behavior sLNvs small ventral lateral neurons structural plasticity suprachiasmatic nuclei vasoactive intestinal peptide

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Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

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Last Updated: May 10, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

Published on: September 17, 2016

Area of Science:

Chronobiology
Neuroscience
Molecular Biology

Background:

Circadian rhythms synchronize physiology and behavior with environmental cycles.
Diverse molecular and cellular processes encode time-of-day information.
The circadian system exhibits plasticity across multiple levels.

Purpose of the Study:

To review examples of circadian system plasticity.
To explore plasticity from cell-autonomous to circuit-based levels.
To define and exemplify different types of circadian plasticity.

Main Methods:

Literature review focusing on circadian plasticity.
Analysis of studies demonstrating daily changes in biological parameters.
Examination of structural circadian plasticity and photoperiod adaptation.

Main Results:

Circadian plasticity encompasses daily parameter changes, structural remodeling, and adaptive adjustments.
Examples illustrate plasticity in clock outputs from neurons to rest-activity cycles.
The circadian system demonstrates significant flexibility in response to environmental cues.

Conclusions:

The circadian system is highly plastic, adapting to daily and seasonal environmental changes.
Understanding circadian plasticity is crucial for synchronizing physiology and behavior.
This review highlights the dynamic nature of circadian regulation.