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Granulocyte-dependent Autoantibody-induced Skin Blistering
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Published on: October 12, 2012

Nonfamilial cherubism.

A Trivedi1, S D Gupta, S Sharma

  • 1Department of Oral Medicine and Radiology, Guru Nanak Dev Dental College, Sunam, Punjab, India.

Journal of the Indian Society of Pedodontics and Preventive Dentistry
|June 4, 2013
PubMed
Summary
This summary is machine-generated.

Cherubism is a rare genetic disorder causing jaw bone swelling in children. This case report details a 12-year-old boy with this progressive, benign condition.

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Area of Science:

  • Genetics
  • Oral and Maxillofacial Surgery
  • Pediatric Dentistry

Background:

  • Cherubism is a rare, inherited condition characterized by benign, progressive enlargement of the jaw bones.
  • It typically manifests in early childhood, presenting as painless facial swelling.
  • The condition involves symmetrical expansion of the maxilla and mandible, often leading to dental abnormalities.

Observation:

  • This report focuses on a 12-year-old male patient.
  • The patient presented with clinical signs consistent with cherubism.
  • The case highlights the progressive nature of the disease into adolescence.

Findings:

  • The case confirms the characteristic symmetrical jaw bone involvement in cherubism.
  • Dental malformations were noted in association with the jaw swelling.
  • The presentation in a 12-year-old extends the typical age range for initial observation.

Implications:

  • Understanding cherubism's progression is crucial for long-term patient management.
  • Early diagnosis and monitoring can help mitigate dental and functional complications.
  • This case contributes to the literature on cherubism, particularly in older children.