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Updated: May 10, 2026

Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
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Published on: May 12, 2022

Home- or community-based programmes for treating malaria.

Charles I Okwundu1, Sukrti Nagpal, Alfred Musekiwa

  • 1Centre for Evidence-based Health Care, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa. ciokwundu@sun.ac.za.

The Cochrane Database of Systematic Reviews
|June 4, 2013
PubMed
Summary
This summary is machine-generated.

Home- and community-based malaria management improves access to antimalarials, potentially reducing childhood mortality. Using rapid diagnostic tests (RDTs) reduces antimalarial overuse and is safe.

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Area of Science:

  • Public Health
  • Infectious Disease Control
  • Global Health Equity

Background:

  • Malaria significantly impacts child and maternal health in sub-Saharan Africa.
  • The World Health Organization (WHO) prioritizes prompt diagnosis and effective treatment for malaria control.
  • Home- and community-based management strategies aim to overcome geographical barriers to malaria treatment.

Purpose of the Study:

  • To evaluate the effectiveness of home- and community-based management strategies for malaria treatment.
  • To assess the impact of these strategies on malaria-related morbidity and mortality.
  • To analyze the safety and efficacy of using rapid diagnostic tests (RDTs) in community settings.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs.
  • Searched multiple databases including Cochrane Library, MEDLINE, EMBASE, and WHO clinical trial registries up to September 2012.
  • Data extraction and risk of bias assessment performed independently by two authors, with evidence quality evaluated using the GRADE approach.

Main Results:

  • Home- or community-based strategies likely increase access to appropriate antimalarials within 24 hours.
  • Moderate evidence suggests these programs may reduce all-cause mortality, particularly in rural Ethiopia.
  • Incorporating RDTs reduced antimalarial prescriptions compared to presumptive treatment, with no increase in adverse outcomes.

Conclusions:

  • Free or subsidized antimalarials through community programs likely improve prompt access.
  • Evidence supports the potential impact of these programs on childhood mortality in suitable settings.
  • RDT integration in community-based malaria management can reduce antimalarial overuse and is safe, preventing undertreatment of other febrile illnesses.