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Prevalence and characterization of thrombocytopenia in pregnancy in Indian women

Singh Nisha1, Dhakad Amita, Singh Uma

  • 1Department of Obstetrics & Gynecology, CSM Medical University, A-172, South City, Raebareli Road, Lucknow, India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|June 5, 2013
PubMed

To find the prevalence and causes of thrombocytopenia during pregnancy. An analytical prospective observational study was conducted in Department of Obstetrics & Gynecology, CSMMU, Lucknow. 1079 antenatal women screened for thrombocytopenia and investigated for cause and management strategies and fetomaternal outcome were recorded. Prevalence of thrombocytopenia was 8.8%. Gestational thrombocytopenia was seen in 64.2%, obstetric in 22.1% and medical in 13.68% cases. Mean platelet count in controls was lower with a significant fall (P < 0.001) in the platelet count as pregnancy advanced. Hypertensive and hepatic disorders were the most common obstetric causes of thrombocytopenia. Mode of delivery was not affected by thrombocytopenia. Maternal morbidity and mortality was seen only in medical and obstetric thrombocytopenia. The low platelet counts and declining trend with increasing gestational age predispose Indian women to risk of thrombocytopenia and a routine platelet count is suggested.

Keywords:
Blood Transfusion MedicineDICGestational thrombocytopeniaHematologyHuman GeneticsMedical thrombocytopeniaMedicine & Public HealthObstetric thrombocytopeniaOncologyPlatelet countPregnancy with ITP

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