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Oophorectomy in breast cancer-controversies and current status

Gurpreet Singh1

  • 1Department of Surgery, Post Graduate Institute of Medical Education & Research, (P.G.I.M.E.R.), Chandigarh, 160012 India.

The Indian Journal of Surgery
|June 5, 2013
PubMed

Keywords:
Breast cancerOophorectomyOvarian ablation

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...