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Correlation between lipid profile and troponin I test results in patients with chest pain in Nepal

Arun Kumar1, Brijesh Sathian

  • 1Associate Professor, Department of Biochemistry, International Medical School, Management and Science University, Shah Alam Campus, Selangor, Malaysia.

Asian Pacific Journal of Tropical Biomedicine
|June 5, 2013
PubMed

Insights

Traditional lipid profiles can help screen for cardiac events when troponin testing isn't available. Elevated cholesterol and triglycerides, with reduced HDL, indicate higher risk in patients with chest pain.

Area of Science:

  • Cardiology
  • Biochemistry

Background:

  • Cardiac events often present with chest pain.
  • Troponin I testing confirms myocardial damage.
  • Lipid profiles assess cardiovascular risk factors.

Purpose of the Study:

  • To evaluate the utility of traditional lipid profiles in identifying cardiac events.
  • To compare lipid profiles in patients with and without confirmed cardiac events.

Main Methods:

  • Retrospective analysis of 430 patients with cardiac ischemia symptoms.
  • Comparison with 165 healthy controls.
  • Analysis of troponin I, total cholesterol, HDL, VLDL, and triacylglycerol levels; LDL calculated via Friedewald's formula.

Main Results:

  • Patients with confirmed cardiac events (positive troponin I) showed significantly higher total cholesterol, triacylglycerol, and LDL levels.
  • These patients also had significantly lower HDL cholesterol levels compared to controls and those with negative troponin tests.

Conclusions:

  • Traditional lipid profiles remain valuable for screening populations at risk for cardiac events.
  • Lipid profiles can be used in settings lacking troponin testing facilities.
Abstract

Keywords:
Cardiac eventChest painLipid profileNepalTroponin

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