Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Outcomes Following Dual-Frequency Noninvasive Monopolar Radiofrequency Treatment for Facial Laxity and Lower Face Lifting: A Prospective Multicenter Study.

Cureus·2026
Same author

Fibroblast-Based Therapies for Wrinkles, Wounds, and Vitiligo: A Comprehensive Review.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2025
Same author

The Addition of Low-Dose Lidocaine and Triamcinolone Reduces the Adverse Effects of 2-Deoxycholate Injection Without Affecting the Long-Term Results.

Journal of cosmetic dermatology·2025
Same author

The History of Dermatology in American Phlebology.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2025
Same author

Histologic Effects of Fractional Lasers and Energy-Based Devices on Intradermally Injected Hyaluronic Acid Filler for Improving Skin Smoothness.

Lasers in surgery and medicine·2024
Same author

NivobotulinumtoxinA in the Treatment of Glabellar Lines With or Without Concurrent Treatment of Lateral Canthal Lines in Two Phase 3 Clinical Trials.

Aesthetic surgery journal·2024

Related Experiment Video

Updated: May 10, 2026

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

Autologous cell therapy: will it replace dermal fillers?

Robert A Weiss1

  • 1Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rweiss@smoothskin.net

Facial Plastic Surgery Clinics of North America
|June 5, 2013
PubMed
Summary
This summary is machine-generated.

Autologous fibroblast therapy offers a novel approach to facial wrinkle treatment, showing promising outcomes and detailing injection techniques and treatment duration for enhanced facial rejuvenation.

More Related Videos

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
04:36

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components

Published on: July 11, 2025

Related Experiment Videos

Last Updated: May 10, 2026

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
04:36

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components

Published on: July 11, 2025

Area of Science:

  • Dermatology
  • Regenerative Medicine
  • Aesthetic Surgery

Background:

  • Facial wrinkles are a common concern, prompting research into effective treatment options.
  • Autologous cell therapy presents a potential alternative to traditional cosmetic procedures.
  • Dermal fillers are a widely used but often temporary solution for wrinkles.

Purpose of the Study:

  • To evaluate the efficacy and safety of autologous fibroblast therapy for facial wrinkles.
  • To compare autologous fibroblast therapy with existing treatments like dermal fillers.
  • To describe the procedural aspects and longevity of autologous cell therapy.

Main Methods:

  • Review of study outcomes for LaViv (autologous fibroblast therapy).
  • Analysis of adverse events associated with the treatment.
  • Description of the autologous cell injection technique.
  • Assessment of the duration of treatment effect.

Main Results:

  • Detailed outcomes of LaViv treatment for facial wrinkles.
  • Summary of reported adverse events, indicating safety profile.
  • Information on the injection methodology for autologous cells.
  • Data on the sustained effect of the therapy over time.

Conclusions:

  • Autologous fibroblast therapy is a viable option for facial wrinkle correction.
  • The study provides insights into the practical application and effectiveness of this cell therapy.
  • Further research may explore long-term results and broader applications.