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Updated: May 10, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Quinazoline derivatives: synthesis and bioactivities
1Department of Chinese Traditional Herbal, Agronomy College, Sichuan Agricultural University, No, 211, Huiming Road, Wenjiang Region, Chengdu, 611130, P, R, China. gaofeng@sicau.edu.cn.
Abstract:
Owing to the significant biological activities, quinazoline derivatives have drawn more and more attention in the synthesis and bioactivities research. This review summarizes the recent advances in the synthesis and biological activities investigations of quinazoline derivatives. According to the main method the authors adopted in their research design, those synthetic methods were divided into five main classifications, including Aza-reaction, Microwave-assisted reaction, Metal-mediated reaction, Ultrasound-promoted reaction and Phase-transfer catalysis reaction. The biological activities of the synthesized quinazoline derivatives also are discussed.
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