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Updated: May 10, 2026

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Epithelial basement membrane dystrophy diagnosed following LASIK surgery]
W Ghouali1, O Sandali, B Ameline
1Centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75571 Paris, France.
Journal Francais D'Ophtalmologie
|June 5, 2013
Summary
Epithelial basement membrane dystrophy (EBMD) can be exacerbated after laser in situ keratomileusis (LASIK) surgery, presenting as corneal irregularities. Early diagnosis with confocal microscopy and treatment with artificial tears and serum eyedrops are crucial for successful outcomes.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Microscopy
Background:
- Laser in situ keratomileusis (LASIK) is a common refractive surgery for myopia correction.
- Pre-operative screening aims to identify conditions that may affect surgical outcomes.
- Epithelial basement membrane dystrophy (EBMD) is a corneal condition that can affect visual quality.
Observation:
- A patient developed decreased vision and photophobia 10 days after bilateral LASIK.
- Slit lamp examination revealed corneal epithelial irregularities.
- Confocal microscopy showed a characteristic appearance consistent with EBMD.
Findings:
- The patient was diagnosed with epithelial basement membrane dystrophy (EBMD) post-LASIK.
- EBMD can be present but undetected before refractive surgery.
- Exacerbation of EBMD following LASIK is an uncommon but possible complication.
Implications:
- Unexplained corneal irregularities after LASIK may indicate an underlying EBMD.
- Confocal microscopy is a valuable tool for diagnosing post-LASIK EBMD.
- Treatment with artificial tears and autologous serum eyedrops can successfully manage this condition.

