Impact of obesity on cardiovascular health
Marzena Chrostowska1, Anna Szyndler, Michał Hoffmann
1Department of Hypertension and Diabetology, Medical University of Gdańsk, Gdańsk, Poland.
Insights
Obesity significantly impacts cardiovascular health, increasing risks for hypertension, heart disease, and stroke. Further research is needed to identify better markers for cardiovascular damage and high-risk individuals.
Area of Science:
- Cardiology
- Public Health
- Metabolic Disorders
Background:
- Obesity is a growing global epidemic.
- It is associated with numerous adverse health outcomes.
- Cardiovascular complications are a major concern in obese populations.
Purpose of the Study:
- To review the multifaceted impact of obesity on cardiovascular health.
- To explore the relationship between obesity, cardiovascular function, and disease.
- To discuss the underlying mechanisms and contributing factors like sleep apnea.
Main Methods:
- Literature review of epidemiological and pathophysiological studies.
- Examination of evidence linking obesity to hypertension, subclinical abnormalities, and overt cardiovascular diseases.
- Discussion of potential mechanisms and the role of sleep apnea.
Main Results:
- Obesity is strongly linked to hypertension and various cardiovascular diseases, including coronary artery disease, heart failure, stroke, and arrhythmias.
- Obesity contributes to subclinical cardiovascular structural and functional abnormalities.
- Sleep apnea is a significant contributor to cardiovascular risk in obese individuals.
Conclusions:
- Obesity poses a substantial threat to cardiovascular health through multiple pathways.
- Improved identification of subclinical cardiovascular damage and high-risk obese individuals is crucial.
- Further research is warranted to elucidate complex pathophysiological links and refine risk stratification.
Abstract:
This review examines the impact of obesity on cardiovascular health. We will review first, relationship between obesity and hypertension. Second, we will describe obesity-related subclinical abnormalities in cardiovascular function and structure. Third, we will summarize evidence linking obesity to overt cardiovascular disease including coronary artery disease, congestive heart failure, stroke, arrhythmias and sudden cardiac death. Fourth, we will discuss the potential mechanisms underlying increased cardiovascular risk in obese subjects. Last, we will discuss contribution of sleep apnea to the link between obesity and cardiovascular disease. Despite recent progress in understanding epidemiologic and pathophysiological links between obesity and cardiovascular disease, several issues remain to be addressed in the future studies. There is a clear need to identify better markers of obesity-related subclinical cardiovascular damage. Furthermore, we should improve identification of obese subjects at highest cardiovascular risk.
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