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Published on: October 4, 2021
Delirium with manic and psychotic features associated with amantadine
1Harvard Medical School, Boston MA 02302, USA.
Abstract:
While clinicians are familiar with psychosis as a complication in the long-term treatment with amantadine, rapid psychiatric complications are of much less concern. In the case presented, severe decompensation in mental status occurred within 48 h of initiation of standard doses of amantadine hydrochloride. Clinicians should be alert not only for delayed complications but also for early-onset mental decompensation in elderly patients with influenza A treated with amantadine.
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