Related Experiment Videos
Muscle lipofuscin content and satellite cell volume is increased after high altitude exposure in humans
M Martinelli1, R Winterhalder, P Cerretelli
1Department of Anatomy University of Bern, Switzerland.
Experientia
|July 15, 1990
Abstract:
Muscle ultrastructural changes during a typical expedition to the Himalayas were analyzed by taking muscle biopsies from seven climbers before and after their sojourn at high altitude (over 5000 m for 8 weeks). M. vastus lateralis samples were analyzed morphometrically from electron micrographs. A quantitative evaluation was made of lipofuscin, satellite cells and myonuclei. Significant increases of the volume densities of lipofuscin (+ 235%) and satellite cells (+ 215%) were observed.