Related Experiment Video
Updated: May 10, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
How to perform local soft-tissue glucocorticoid injections?
J W G Jacobs1, J M R Michels-van Amelsfort
1Department of Rheumatology & Clinical Immunology, F02.127, University Medical Center Utrecht, Box 85500, 3508 GA Utrecht, The Netherlands. J.W.G.Jacobs@UMCUtrecht.nl
Local glucocorticoid injections can benefit inflammatory rheumatic diseases and soft-tissue lesions, even without an underlying rheumatic condition. This review covers injection therapy for these soft-tissue issues and nerve compression syndromes.
Area of Science:
- Rheumatology
- Orthopedics
- Sports Medicine
Background:
- Periarticular soft-tissue inflammation (tendons, bursae, ligaments) is common in rheumatic diseases.
- Soft-tissue irritation can also occur independently of rheumatic conditions.
- Local glucocorticoid injections are frequently used for these lesions.
Purpose of the Study:
- To review the efficacy of local glucocorticoid injection therapy.
- To cover primary and secondary soft-tissue lesions.
- To include nerve compression syndromes in the review.
Main Methods:
- Literature review of local injection therapy for soft-tissue lesions.
- Review of evidence for glucocorticoid injections.
- Inclusion of nerve compression syndromes.
Main Results:
- Limited literature evidence exists for local glucocorticoid injections.
- Glucocorticoid injections are often beneficial for soft-tissue lesions.
- The review synthesizes current knowledge on injection therapy.
Conclusions:
- Local glucocorticoid injections are a valuable treatment option.
- Effective for both rheumatic and non-rheumatic soft-tissue inflammation.
- Also relevant for managing nerve compression syndromes.
More Related Videos
08:04A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
Published on: January 24, 2020
05:18Collection of Skeletal Muscle Biopsies from the Superior Compartment of Human Musculus Tibialis Anterior for Mechanical Evaluation
Published on: September 27, 2020
Related Concept Videos
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...